Viagra Effects on Coagulability (Bleeding Disorders and Viagra, Sickle Cell Disease)
Viagra is one of the best drugs to treat sexual dysfunction and increase potency. It acts an hour after taking the pill and acts for up to four hours. Under the influence of Viagra, the muscle tissue of the penis relaxes, oxygen saturates the blood, premature ejaculation is suppressed, and sensitivity is increased.
The medication stimulates an erection and prolongs sexual intercourse by several times. With the regular use of the drug, most men note the complete elimination of the problem of early ejaculation, increased sexual activity, as well as an enhanced production of seminal fluid. Despite the high effectiveness of the drug, in some cases, Viagra causes adverse reactions.
Due to the fact that the agent stimulates blood circulation and puts a high load on the heart muscle, an optimal dose of the drug should be carefully prescribed in each individual case.
Effects of Viagra on Blood Vessels and Circulation
The action of Viagra is distinguished by a selective effect and is directed to the vessels of the penis only. This drug corrects violations of their functionality. It accelerates the reproduction of nitric oxide and inhibits the production of the enzyme phosphodiesterase. Nitric oxide saturates the blood with oxygen and helps relax the vessels and walls of the arteries. Thus, the vessels expand and the normal blood circulation of the penis restores. In addition, nitric oxide relaxes the smooth muscles of the cavernous bodies of the genital organ. Thus, the muscles at a root of the penis relax and the male organ is filled with blood, which leads to an erection. Immediately after this, the veins on the outflow narrow, which prevents the blood from going back. Also, the male organ becomes more sensitive and responds better to sexual arousal.
Phosphodiesterase has the opposite effect. It allows blood to flow from the genitals after ejaculation and thus the penis becomes flaccid.
Coagulability and Viagra
Thick blood is an alarming symptom, which is a consequence of some disorders in the body and is also a harbinger of some diseases. Men who have problems with coagulability and suffer from bleeding disorders should be careful when taking Viagra.
If you strictly adhere to the prescribed dosage, Viagra side effects are not significant.
The phosphodiesterase enzyme is contained in the muscular tissues of the cavernous bodies of the penis, the smooth muscles of the vessels, skeletal muscles, internal organs, and platelets.
Viagra suppresses this enzyme, as a result of which peripheral vessels expand and blood coagulability decreases.
Therefore, the following symptoms are typical:
- The appearance of blush on the cheeks and neck
- Headaches or dizziness
- Deterioration of indulgence and nasal congestion
Recently, scientists dealing with the treatment of malignant tumors discovered that Viagra has a coagulating property, similar to laser exposure. Coagulation is a process of clotting, which makes blood jelly-like, forming a blood clot. Thus, the cancerous tumors under the influence of Viagra significantly decrease in size.
Bleeding Disorders and Viagra
Under the action of sildenafil, the main active substance of Viagra, the antiplatelet effect of the donor nitrogen oxide, sodium nitroprusside, is enhanced on platelets. There is no information on the safety of the use of sildenafil in patients with peptic ulcer, duodenal ulcer, and bleeding disorders. For these reasons, you need to use Viagra very carefully.
The probability of nasal bleeding in a patient who has pulmonary hypertension on the background of a diffuse pathology of connective tissue is somewhat higher than in a patient with primary hypertension. Thus, when using sildenafil in such patients, this frequency is 12.9% with placebo is 0%.
In patients with primary pulmonary hypertension, this rate is 3% when taking sildenafil and 2.4% with placebo. When taking sildenafil with antagonists of vitamin K, the possibility of bleeding is higher than in people who do not take it.
Thus, the incidence of nasal bleeding in patients with impaired erectile function is 8.8% when taking the medication, while in patients who do not take an antagonist of vitamin K, the rate is 1.7%.
Sickle Cell Disease
Sickle cell disease is an autosomal recessive superdominant genetic blood disease characterized by the presence of abnormal red blood cells (erythrocytes) of a resistant sickle shape.
Due to the fact that cells are sickle-shaped, their flexibility and elasticity are reduced, which increases the risk of various complications. The cause of sickle cell disease is mutations in the hemoglobin gene. As a result, the life expectancy is reduced. On average, it is 42 years for men. Thus, men suffering from the sickle-cell disease should inform their doctor about their illness before taking Viagra.
Viagra is an indispensable assistant in the fight against impotence for many men, but, like all medications, it should be used with caution. It is necessary to adhere to all the rules of application and observe the dosage. This will help not only achieve the desired result but also stay healthy.
