Cialis Daily vs. Regular Cialis: What to choose?

Regular use of drugs like Viagra and Cialis can restore the ability of erection in patients with erectile dysfunction. The effect can sit for long after the end of therapy, according to this comparatively new research. Early in 2009, tadalafil (commercialized under the brand name of Cialis) became available in therapeutic dose of 2.5 mg, and the previously existing dose of 5 mg received a makeover and started to be additionally released as the second variant of the pill intended for a regular daily use – as opposed to on-demand pills containing 5 mg, 10 mg or 20 mg of tadalafil. With so much of a form diversity, patients expectedly find themselves somewhat confused. Canadian Online Pharmacy mycanadianpharmacyrx.com explains the purpose of two different approaches that evolved in treatment with tadalafil.

Regular use of PDE5 inhibitors perpetuate their effects after the drug’s action is over

For a man to be able to get an erection requires both sexual stimulation and blood supply to the penis is sufficient. Around 30 times as much blood must flow to the erectile tissue in the penis necessitates to develop an erection as compared to the normal state.

Tadalafil and related compounds act by inhibiting the enzyme phosphodiesterase type 5 (PDE5), thereby reinforcing the signalling of nitric oxide from endothelial cells of the blood vessel wall. Nitric oxide has a relaxing effect on the smooth muscle around blood vessels and improves blood flow.

Normally impotence drugs such as Viagra (sildenafil) and Cialis (tadalafil) are used only if needed directly before the anticipated sexual activity. The drugs increase blood flow into the penis during sexual stimulation and help erection to develop. The effect lasts as long as the drug remains in the body.

A new evidence provided by a recent research indicates that more frequent use can result in lasting improvements in the ability to obtain an erection, in addition to those that the medication offers as a result of the application as intended by the original instructions. The effect may persist months after the end of treatment, suggesting that patients could be cured from impotence.

For many men with erectile dysfunction the ability to obtain an erection is an important part of their virile self-image. For them, it may be valuable to eventually avoid having to take the tablets. It is important to find out the types and severity of erectile failure that treatment can work, says Petter Hedlund, associate professor of clinical pharmacology and chair of the scientific committee of the European Society for Sexual Medicine.

So far, only small studies done where the new treatment principle has been tried. In 2007, German scientists published a non-blinded study of 112 patients with vascular erectile dysfunction who were drawn to either take sildenafil daily or use the drug if necessary, in accordance with normal procedure. After a year ending treatment, and the participants were not to take the drug for four weeks.

60% of patients receiving regular treatment restored their erectile capacity without the use of drugs. The corresponding figure in the control group was 8 percent. The patients who received regular treatment and regained the ability to achieve erection was followed up by a further five months’ improvement without access to medicines. By 2011 when the last examination was taken, all but one patients still retained the ability to erection.

Other smaller studies of regular dosage of sildenafil and tadalafil have shown similar lasting effects in different groups of patients with erectile dysfunction. Meanwhile, a Finnish unpublished double-blind study demonstrated that chronic administration of sildenafil was not effective in patients after prostate cancer surgery.

The accumulated benefits of Cialis Daily

It is based on the data collected from the German study that the developers of tadalafil (you know it commercially as Cialis) started releasing the dosage option of Cialis 2.5 mg and Cialis 5 mg Daily in addition to the previously available Cialis 5 mg, Cialis 10 mg and Cialis 20 mg. And although one should be aware that the research is still in early stages, Cialis Daily pills are gaining popularity because of their proven efficacy and reliability.

This new treatment principle was established for another drug of the same class of PDE5 inhibitor, Cialis (tadalafil), after the outcomes assessed according to the same evidence-based principles that apply to all new treatments in medicine. In addition to the pure patient benefits however, there are several interesting scientific aspects of the new results.

A regular intake of Cialis 2..5 mg or Cialis 5 mg (an exact dosing option is subject to prescriber’s appointment) enables the receiving person to successfully attempt sexual acts between doses taken each day. An important safety note here is that it is contraindicated to use both forms of Cialis, ‘on demand’ and ‘daily’, in conjunction. Severe side effects linked to overdose occurrence are most probable. When wanting to switch from regular posological medicating to the doses taken as needed, prescriber should be consulted before discontinuation of the current course.

The effects of Cialis Daily are experienced after 4 to 5 days in the majority of patients. Here again, this timespan can be different from one individual to another, subject to many factors that influence the effect onset of tadalafil.

Cialis Daily used in BPH patients

Erectile dysfunction is often a result of a general effect on the vascular system in patients with hypertension, diabetes and dyslipidemia. It has been speculated that these types of vasodilating drugs could be used to improve vascular function in these patients. According to this theory, one would first see the effect in the small vessels, such as the erectile tissue in the penis, which is supported by the current results.

This characteristic of tadalafil is what stands behind the use of Cialis 2.5 mg and Cialis 5 mg in persons suffering from benign prostatic hyperplasia (BPH), a condition that involves a non-malignant growth of prostate gland tissues. Regular use of tadalafil in smaller dosages in patients who respond well to the therapy is considered to have health benefits over higher doses of the same drug. As in many other cases, the rationale behind a strong medical bias towards lower-dosage pills is a lower risk of adverse events posed by those latter.

Benefits of Cialis Daily

The most obvious benefit of Cialis pills containing 2.5 mg and 5 mg of tadalafil is based on the safety of the smaller doses. The risk of developing side effects diminish proportionally to the decrease in the dose. This is, however, to a certain extent counterbalanced by a regular exposure to tadalafil effects day in, day out.

Patients receiving this pattern of treatment report being more confident in face of anticipated sexual activity. Ingesting smaller but regularly distributed doses of tadalafil helps them to restore self-worth and curb symptoms of anxiety associated with sexual performance and the fear of failure.

The boost in release of nitric oxide that is brought on by tadalafil and spread evenly throughout medicating history has a beneficial effect on the prostate gland, preventing many conditions associated with its abnormal growth, and inter alia, one of the most common forms of cancer – prostate cancer. These benefits are especially essential in patients aged above 40 years.

The use of Cialis 5 mg is preferred in certain populations due to the safety reasons. Thus, in persons with kidney or liver troubles, revision of tadalafil dose towards the lower end of the spectrum is required. The same is preferable in a number of other comorbidities, as well as in geriatric population. Smaller Cialis dose will also minimize the risk of possible side effects in cases of adjacent therapies (when the use of Cialis coincides with taking medications for other conditions; however, in cases like that on-demand version of Cialis with a reduced dose of tadalafil should be the therapy of choice).

When regular Generic Cialis doses are a better call

Not everyone, however, finds that this new approach will benefit them. Most men think that medication ‘on demand’ works well. Taking the pills regularly for a long period of time may seem unnecessary in an otherwise healthy man. Besides, many patients feel like administrating chemical substances without any immediate necessity is counterproductive in terms of their general health.

The efficacy of smaller doses of tadalafil used in Cialis Daily do not work for patients with severely compromised erectile function. Therefore, elevated doses of Cialis, such as Cialis 10 mg or Cialis 20 mg should be appointed under medical surveillance. The average minimal effective dose in ED patients is Cialis 10 mg, and that for BPH patients is Cialis 20 mg with potential increase up to Cialis 40 mg taken once a day.

Based on personal unique circumstances of everyone’s private life, patients should have the last say on which type of medicating best fits their requirements for ED therapy. Thus, if a man engages in sexual activity only occasionally due to the absence of a long-term commitment in relationships, proceeding from his sexual temperament and constitution (or those of his partner) and other variables, it appears to be unnecessary to commit to a regularly scheduled ingestion of tadalafil.

Canadian Online Pharmacy highlights that whichever dosing option of Cialis sounds more appealing to you, the approval of a qualified healthcare provider is required at all events. We remind you that Canadian Pharmacy subscribers have a free access to medical counseling online in case of any questions related to these or other healthcare products; such counselling though is just a preliminary estimation and guidance that should be followed on by a physical presence at your practitioner’s office.