Caverta 50/100mg at My Canadian Pharmacy: Definition, Applications, Contraindications and Side Effects, Health Effects And Benefits, Food And Drug Interactions, Caverta Vs. Kamagra, Safety Note
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CONTENT
- Caverta Definition
- Caverta 100mg Applications
- Contraindications: Is Caverta Right For Me?
- Health Effects And Benefits
- Possible Caverta Side Effects
- Caverta Food And Drug Interactions
- Caverta Vs. Kamagra
- Safety Note On Caverta
Caverta (Sildenafil Citrate) Definition
Sildenafil is a phosphodiesterase type 5 inhibitor effective in treating impotence, a problem with high psychological and social impact of the complex multifactorial nature which, however, requires an integrated approach, not only drug. It has the advantage of being administered orally. The drug shows its effect only when the sexual interest is still intact. The action appears usually after one hour. Altogether it is well tolerated. Potentiates the hypotensive effect of nitrates, so its administration is contraindicated in patients who are taking nitrates in any pharmaceutical formulation.
Caverta 100mg Applications
Caverta is used in ED (erectile dysfunction) as a solution for a temporary erectile restoration. Sildenafil, the medicinal basis for Caverta, can also be used to treat PAH (pulmonary arterial hypertension) and a number of other off-label conditions according to prescriber’s instructions.
Sildenafil dose contained in Caverta is maximal, which promotes the drug to the status of an ED treatment engaged in especially difficult cases, such as, for instance, full impotence – an absolute inability to achieve erectile hardness.
Caverta Contraindications: Is Caverta Right For Me?
Do not take Caverta tablets in the following cases:
- In case of taking medications called nitrates, as this combination may result in a decrease in your potentially dangerous blood pressure. Tell your doctor In case of taking any of these medicines that are often used to relieve angina (or “chest pain”). If in doubt, seek the advice of your doctor or pharmacist.
- In case of using any of the medications known as nitric oxide donors such as amyl nitrite (the so-called ‘poppers’), as this combination can also cause a decrease in potentially dangerous blood pressure.
- In case of allergy (hypersensitive) to sildenafil or to any of the other ingredients Caverta.
- If you experience serious cardiac or hepatic problems.
- If you have recently experienced a stroke or a heart attack, or if your blood pressure is low.
- If you suffer from rare hereditary eye diseases (such as retinitis pigmentosa).
- If you have ever had vision loss brought on by non-arteritic anterior ischemic neuropathy (NAION).
- In case of not suffering from ED.
- In case you are a female patient.
- In case of under 18 years of age.
Read also: Viagra, Cialis and High Blood Pressure
Caverta 100mg Health Effects And Benefits
Caverta has shown efficacy in 82% of men with various medical history backgrounds. Below you will find information on the use of Caverta in certain specific populations.
Patients with diabetes mellitus
14 of the studies included in the review included diabetic patients while two studies exclusively enrolled patients with this disease. Diabetic patients treated with sildenafil had a significantly more complete reports than those who received placebo. These patients also experienced an improvement in erectile ability.
Patients with hypertension and cardiovascular diseases (other than diabetes)
The studies included in the meta-analysis included patients with cardiovascular disease (myocardial ischemia, peripheral circulation disease, hypertension) stabilized while several studies have specifically evaluated the efficacy and safety of sildenafil in patients with stable cardiovascular disease severity which would not constitute a contraindication to a normal sexual activity. They were excluded from the study patients treated with nitrates (in which the drug is contraindicated). Sildenafil has proved effective and safe, not changing the hemodynamic variables and not interfering with drug therapy that patients taking.
Patients with bone marrow traumas
Two studies have evaluated the efficacy of sildenafil in the treatment of erectile dysfunction associated with traumatic spinal cord injury. In both studies, sildenafil has been proven effective in improving erectile ability. The number of comprehensive reports was significantly longer for patients who received the drug compared to the group who took the placebo.
Patients with spina bifida
A blinded, randomized, controlled, cross-over, small (19 patients) evaluated the efficacy of sildenafil in the treatment of erectile dysfunction associated with spina bifida. Patients treated with the drug have noted significant improvement of erection capacity. The study did not evaluate the ability of patients to have a full report.
Radical prostatectomy
Data regarding the efficacy of sildenafil in this subset of patients is limited. The drug appears to be significantly more effective in improving erectile capacity compared to placebo and increasing the ability to have a full report in treated patients; However, the answer is less than other categories of patients.
Patients with depression
A recent review evaluated the efficacy of sildenafil in patients with erectile dysfunction associated with depression and / or taking SSRIs. They were considered a total of 13 studies, 3 of which have specifically evaluated the efficacy of the drug in this group of patients. The data seem to demonstrate the efficacy of sildenafil in patients with minor depression is not receiving any medical treatment, that in subjects in which the depression is adequately controlled dall’SSRI (without resolving the associated erectile dysfunction), that in cases where erectile dysfunction is secondary to treatment with SSRIs. Another randomized double-blind study of 90 patients evaluated the efficacy of sildenafil (50-100mg) in the treatment of erectile dysfunction associated with the use of SSRIs. The study confirmed the results obtained in previous studies: sildenafil improved both erectile function that other aspects of sexual function.
Possible Caverta Side Effects
Abnormalities in color vision can be varied and depend on component(s) involved in visual perception: can there be a worse damage to the three types of cones (retinal receptors individually sensitive to red, green, blue), a more widespread retinal damage, impaired nerve transmission at the optic nerve or disorders of the visual centers that compromise the visual information transmission. Some color vision disorders are hereditary, such as color blindness. In these cases, the default is binocular, symmetrical, not felt by the patient and unchangeable.
When a patient complains of a disturbance in color vision it is necessary to do everything possible to prevent other ocular disorders or severe general. When you suspect a cause iatrogenic, you must immediately reduce the dose or suspend it entirely, to avoid serious damage and / or irreversible effects.
Caverta Food And Drug Interactions
Caverta prescriber should be made aware of every healthcare item you currently take, be it legend, herbal or OTC in its nature. When you are already on sildenafil therapy, inform your physician if you plan to add any new drugs to the list according to prescriptions by other healthcare providers. Caverta will interact with drugs used to treat chest pain (angina) that are based on nitrates, as well as some recreational nitrate-based drugs called ‘poppers’, certain HIV drugs (antiretroviral drugs) and alpha-blockers.
In patients receiving HIV drugs and alpha-blockers sildenafil dose adjustment is required. Such individuals should use the minimal dose of sildenafil, which is 25mg. A daily dose of alpha-blockers should be taken prior to Caverta intake, well in advance (at least 2 hours before sildenafil).
Fatty foods and alcohol will inhibit the effects of Caverta, and grapefruit / grapefruit juice will slow down elimination of the drug and aggravate side effects. Neither combination is recommended.
Caverta Vs. Kamagra
Caverta and Kamagra have a common denominator, which is sildenafil citrate, as their main pharmacological component. Caverta and Kamagra contain equal amount of the principal component, which is sildenafil 100mg. This explains complete correspondence of their applications, health outcomes, side effects and other meaningful pharmacokinetic and pharmacodynamic characteristics. Clinical efficacy of both Caverta and Kamagra is estimated at 82% in male patients aged below 60 years of age.
Safety Note On Caverta
Medications associated with color vision disorders belong to various classes and primarily cause neuropathy, retinopathy or changes in the signal transmission. The pathogenic mechanisms are not always known.
Already in the pivotal studies there were reported transient changes in color perception in patients treated with sildenafil. In a systematic review of 14 clinical trials involving a total of 3,780 patients, the incidence of visual disturbances induced by sildenafil was 3% at doses of between 25mg and 100mg compared with 0.8% of placebo-treated patients. The predominant color is blue or blue-green, sometimes with color change to pink or yellow; some patients have claimed to detect the dark colors even darker, others have reported difficulties in distinguishing colors. These effects usually occur at 1-2 hours after taking the sildenafil and are reversible (usually disappear within 3-6 hours). There were also dose dependent and are due to the inhibitory effect against phosphodiesterase, an enzyme also involved in retinal phototransduction. They do not seem associated with serious eye injuries, but you have to pay special attention if the patient suffers from a degenerative disorder of the retina. Even tadalafil may alter the vision of colors, resulting in particular cyanopsia (predominance of blue), but with a lower frequency compared to the sildenafil. Disturbance of color vision have also been reported with the use of vardenafil.